Genomics

Whole-genome, whole-exome, and single-cell DNA sequencing.

Whole-genome sequencing

Planned: experimental design, QC, alignment, variant calling, CNV/SV analysis, annotation, and cohort analysis.

Whole-exome sequencing

Planned: capture-specific QC, coverage, germline and somatic variants, and limitations.

Single-cell DNA sequencing

Planned: amplification bias, allele dropout, copy-number inference, phylogeny, and tumor evolution.